GENETIC SUSCEPTIBILITY TO ENVIRONMENTAL CARCINOGENESIS
GSEC: An International Collaborative Project
GSEC Publications

Varela-Lema, L;Taioli, E*; Ruano-Ravina, A; Barros-Dios, JM; Anantharaman, D; Benhamou,  S; Boccia S; Bhisey RA; Cadoni, G; Chen, CJ; Coutelle C ; Foulkes W.D; Goloni-Bertollo, EM; Hatagima A, Hayes RB; Katoh, T; Koifman S, Lazarus P; Manni JJ; Mahimkar M, Morita S; Park J; Pavarino Bertelli EC; Ribeiro EMSF; Roy B; Spitz, M; Strange RC; Wei Q; Ragin, C. Meta- and pooled analysis of GSTM1 and CYP1A1 polymorphisms and oral and pharyngeal cancers: a HuGE-GSEC review. Genetics in Medicine, 2008 January; In Press

Boccia S, Hung R, Ricciardi W, Gianfagna F, Ebert M.P.A., Fang J-Y,  Gao CM, Götze T, Graziano F, Lacasaña M, Lin D, López-Carrillo L, Qiao Y-L, Hongbing Shen H, Rachael Stolzenberg-Solomon R, Toshiro Takezak Ti, Weng Y-R, Zhang F-F, van Duijn C.M., Boffetta P, Taioli E. Meta- and Pooled Analyses of the Methylenetetrahydrofolate Reductase C677T and A1298C Polymorphisms and Gastric Cancer Risk: A Huge-GSEC Review. Am J Epidemiol. 2007 Dec 27; [Epub ahead of print]

Kellen E, Hemelt M, Broberg K, Golka K, Kristensen VN, Hung RJ, Matullo G, Mittal RD, Porru S, Povey A, Schulz WA, Shen J, Buntinx F, Zeegers MP, Taioli E. Pooled Analysis and Meta-analysis of the Glutathione S-Transferase P1 Ile 105Val Polymorphism and Bladder Cancer: A HuGE-GSEC Review. Am J Epidemiol. 2007 Apr 2

Taioli E, Benhamou S, Bouchardy C, Cascorbi I, Cajas-Salazar N, Dally H, Fong KM, Larsen JE, Le Marchand L, London SJ, Risch A, Spitz MR, Stucker I, Weinshenker B, Wu X, Yang P. Myeloperoxidase G-463A polymorphism and lung cancer: a HuGE genetic susceptibility to environmental carcinogens pooled analysis. Genet Med. 2007 Feb;9(2):67-73.

Paracchini V, Raimondi S, Gram IT, Kang D, Kocabas NA, Kristensen VN, Li D, Parl FF, Rylander-Rudqvist T, Soucek P, Zheng W, Wedren S, Taioli E. Meta- and pooled analyses of the cytochrome P-450 1B1 Val432Leu polymorphism and breast cancer: a HuGE-GSEC review. Am J Epidemiol. 2007 Jan 15;165(2):115-25. Epub 2006 Oct 19. Review.

Raimondi S, Paracchini V, Autrup H, Barros-Dios JM, Benhamou S, Boffetta P, Cote ML, Dialyna IA, Dolzan V, Filiberti R, Garte S, Hirvonen A, Husgafvel-Pursiainen K, Imyanitov EN, Kalina I, Kang D, Kiyohara C, Kohno T, Kremers P, Lan Q, London S, Povey AC, Rannug A, Reszka E, Risch A, Romkes M, Schneider J, Seow A, Shields PG, Sobti RC, Sorensen M, Spinola M, Spitz MR, Strange RC, Stucker I, Sugimura H, To-Figueras J, Tokudome S, Yang P, Yuan JM, Warholm M, Taioli E. Meta- and Pooled Analysis of GSTT1 and Lung Cancer: A HuGE-GSEC Review. Am J Epidemiol. 2006;

Ioannidis JP, Gwinn M, Little J, Higgins JP, Bernstein JL, Boffetta P, Bondy M, Bray MS, Brenchley PE, Buffler PA, Casas JP, Chokkalingam A, Danesh J, Smith GD, Dolan S, Duncan R, Gruis NA, Hartge P, Hashibe M, Hunter DJ, Jarvelin MR, Malmer B, Maraganore DM, Newton-Bishop JA, O’Brien TR, Petersen G, Riboli E, Salanti G, Seminara D, Smeeth L, Taioli E, Timpson N, Uitterlinden AG, Vineis P, Wareham N, Winn DM, Zimmern R, Khoury MJ; Human Genome Epidemiology Network and the Network of Investigator Networks Road map for efficient and reliable human genome epidemiology. Nat Genet. 38(1):3-5, 2006

Taioli E. Biomarkers of genetic susceptibility to cancer: applications to epidemiological studies. Future Oncol. 1(1):51-6, 2005

Raimondi S, Boffetta P, Anttila S, Brockmoller J, Butkiewicz D, Cascorbi I, Clapper ML, Dragani TA, Garte S, Gsur A, Haidinger G, Hirvonen A, Ingelman-Sundberg M, Kalina I, Lan Q, Piera Leoni V, Le Marchand L, London SJ, Neri M, Povey AC, Rannug A, Reszka E, Ryberg D,. Risch A, Romkes M, Ruano-Ravina A, Schoket B, Spinola M, Sugimura H, Wu X, Taioli E. Metabolic gene polymorphism and lung cancer risk in non-smokers: an update of the GSEC study. Mut Res. 592:45-57 2005

Vineis P, Veglia F, Anttila S, Benhamou S, Clapper ML, Dolzan V, Ryberg D, Hirvonen A, Kremers P, Le Marchand L, Pastorelli R, Rannug A, Romkes M, Schoket B, Strange RC, Garte S, Taioli E. CYP1A1, GSTM1 and GSTT1 polymorphisms and lung cancer: a pooled analysis of gene-gene interactions. Biomarkers 9:298-305, 2004

Raimondi S, Benhamou S, Coutelle C, Garte S, Hayes R, Kiemeney L, Lazarus P, Marchand LL, Morita S, Povey A, Romkes M, Zijno A, Taioli E. Association of metabolic gene polymorphisms with alcohol consumption in controls. Biomarkers 9:180-9, 2004

Vogl FD, Taioli E, Maugard C, Zheng W, Pinto LF, Ambrosone C, Parl FF, Nedelcheva-Kristensen V, Rebbeck TR, Brennan P, Boffetta P. Glutathione S-transferases M1, T1, and P1 and breast cancer: a pooled analysis. Cancer Epid. Biom. Prev. 13:1473-9, 2004

Taioli E, Pedotti P, Garte S. Importance of allele frequency estimates in epidemiological studies. Mutat Res. 567:63-70, 2004

Smits KM, Benhamou S, Garte S, Weijenberg MP, Alamanos Y, Ambrosone C, Autrup H, Autrup JL, Baranova H, Boffetta P, Bouchardy C, Brockmoller J, Butkiewicz D, Cascorbi I, Clapper ML, Coutelle C, Daly A, Muzi G, Dolzan V, Farker K, Golka K, Haugen A, Hein DW, Hildesheim A, Hirvonen A, Hsieh L, Ingelman-Sundberg M, Kalina I, Kang D, Katoh T, Kihara M, Ono-Kihara M, Kim H, Kiyohara C, Kremers P, Lazarus P, Le Marchand L, Lechner MC, London S, Manni JJ, Maugard CM, Morgan GJ, Morita S, Nazar-Stewart V, Nedelcheva Kristensen V, Oda Y, Parl FF, Peters WHM, Rannug A, Rebbeck T, Ribeiro Pinto LF, Risch A, Romkes M, Šalagovic J, Schoket B, Seidegard J, Shields PG, Sim E, Sinnett D, Strange RC, Stucker I, Sugimura H, To-Figueras J, Vineis P, Yu MC, Zheng W,, Pedotti P, Taioli E. Association of  metabolic gene polymorphisms with tobacco consumption in healthy controls. Int J Cancer 110:266-70, 2004.

Hashibe M, Brennan P, Strange RC, Bhisey R, Cascorbi I, Lazarus P, Oude Ophuis MB, Benhamou S, Foulkes WD, Katoh T, Coutelle C, Romkes M, Gaspari L, Taioli E, Boffetta P. Meta- and pooled analyses of GSTM1, GSTT1, GSTP1, and CYP1A1 genotypes and risk of head and neck cancer. Cancer Epidem. Biom. Prev. 12: 1509-17, 2003.

Le Marchand L, Guo C, Benhamou S, Bouchardy C, Cascorbi I, Clapper ML, Garte S, Haugen A, Ingelman-Sundberg M, Kihara M, Rannug A, Ryberg D, Stucker I, Sugimura H, Taioli E. Pooled analysis of the CYP1A1 Exon 7 polymorphism and lung cancer (United States). Cancer Causes Control 14: 339-46, 2003.

Hung RJ., Boffetta P., Brockmöller J., Butkiewicz D., Cascorbi I., Clapper M. L., Garte S., Haugen A., Hirvonen A., Kalina ., Le Marchand L., London S. J., Rannug A., Romkes M., Schoket B., Gaspari L. and Taioli E. CYP1A1 and GSTM1 genetic polymorphisms and lung cancer risk in Caucasian nonsmokers: a pooled analysis. Carcinogenesis  24: 875-82, 2003.

Smits K. M., Gaspari L., Weijenberg M. P., Dolzan V., Golka K., Roemer H. C., Nedelcheva kristensen V., Lechner M. C., Seidegard J., Strange R. C. and Taioli E. Interaction between smoking, GSTM1 deletion and colorectal cancer: results from the GSEC study. Biomarkers 8: 299-310, 2003.

Vineis P., Veglia F., Benhamou S., Butkiewicz D., Cascorbi I., Clapper M. L., Dolzan V., Haugen A., Hirvonen A., Ingelman-Sundberg M., Kihara M., Kiyohara C., Kremers P., Le Marchand L., Ohshima S., Pastorelli R., Rannug A., Romkes M., Schoket B., Shields P., Strange R. C., Stucker I., Sugimura H., Garte S., Gaspari L., Taioli E. CYP1A1 T3801C polymorphism and lung cancer: a pooled analysis of 2,451 cases and 3,358 controls. Int. J. Cancer 104: 650-657, 2003.

Taioli E., Gaspari L., Benhamou S., Boffetta P., Brockmoller J., Butkiewicz D., Cascorbi I., Clapper M.L., Dolzan V., Haugen A., Hirvonen A., Husgafvel-Pursiainen K., Kalina I., Kremers P., Le Marchand L., London S., Rannug A., Romkes M., Schoket B., Seidegard J., Strange R.C., Stucker I., To-Figueras J. and Garte S. Polymorphisms in CYP1A1, GSTM1, GSTT1 and lung cancer below the age of 45 years. Int. J. Epidemiol. 32: 60-63, 2003.

Benhamou S., Lee W. J., Alexandrie A., Boffetta P., Bouchardy C., Butkiewicz D., Brockmöller J., Clapper M. L., Daly A., Dolzan V., Ford J., Gaspari L., Haugen A., Hirvonen A., Husgafvel-Pursiainen K., Ingelman-Sundberg M., Kalina I., Kihara M., Kremers P., Le Marchand L., London S. J., Nazar-Stewart V., Ono-Kihara M., Rannug A., Romkes M., Ryberg D., Seidegard J., Shields P., Strange R. C., Stücker I., To-Figueras J., Brennan P., and Taioli E. Meta- and pooled analyses of the effects of glutathione S-Transferase M1 polymorphism and smoking on lung cancer risk. Carcinogenesis 23: 1343-1350, 2002.

Lee W. J., Brennan P., Boffetta P., London S. J., Benhamou S., Rannug A., To-Figueras J., Ingelman-Sundberg M., Shields P., Gaspari L. and Taioli E. Microsomal epoxide hydrolase polymorphisms and lung cancer risk: a quantitative review. Biomarkers, 7, 3: 230-241, 2002.

Ingelman-Sundberg M., Oscarson M., Daly AK., Garte S.and Nebert DW. Human Cytochrome P450 (CYP) Genes: A Web page for the Nomenclature of Alleles. Cancer Epidem. Biom. Prev. 10: 1307-1308, 2001. Stücker I., Boffetta P., Anttila S., Benhamou S., Hirvonen A., London S., and Taioli E.. Lack of Interaction between Asbestos Exposure and Glutathione S-Transferase M1 and T1 genotype in lung carcinogenesis. Cancer Epidem. Biom. Prev. 10: 1253-1258, 2001.

Vineis P., Marinelli D., Autrup H., Brockmoller J., Cascorbi I., Daly AK., Golka H., Okkels K., Risch A., Rothman N., Sim E., Taioli E. Current smoking, occupation, N-acetyltransferase-2 and bladder cancer: a pooled analysis of genotype-based studies. Cancer Epidem. Biom. Prev. 10: 1249-1252, 2001.

Garte S, Gaspari L, Alexandrie AK, Ambrosone C, Autrup H, Autrup JL, Baranova H, Bathum L, Benhamou S, Boffetta P, Bouchardy C, Breskvar K, Brockmoller J, Cascorbi I, Clapper ML, Coutelle C, Daly A, Dell’Omo M, Dolzan V, Dresler CM, Fryer A, Haugen A, Hein DW, Hildesheim A, Hirvonen A, Hsieh LL, Ingelman-Sundberg M, Kalina I, Kang D, Kihara M, Kiyohara C, Kremers P, Philip Lazarus P, Le Marchand L, Lechner MC, van Lieshout EMM, London S , Manni JJ, Maugard CM, Morita S, Nazar- Stewart V, Noda K, Oda Y, Parl FF, Pastorelli R, Persson I, Peters WHM, Rannug A, Rebbeck T, Risch A, Roelandt L, Romkes M, Ryberg D, Salagovic J, Schoket B, Seidegard J, Shields PG, Sim E, Sinnet D, Strange RC, Stucker I, Sugimura H, To-Figueras J, Vineis P, Yu MC, and Taioli E. Metabolic gene frequencies in control populations. Cancer Epidem. Biom. Prev. 10:1239-1248, 2001.

Gaspari L., Marinelli D. and Taioli E. International Collaborative Study on Genetic Susceptibility to Environmental Carcinogens (GSEC): an Update. Int. J. Hyg. Environ. Health. 204: 39-42, 2001.

Taioli E. International Collaborative Study on Genetic Susceptibility to Environmental Carcinogens. Cancer Epidem. Biom. Prev. 8:727-728, 1999.

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